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What to Expect When Switching to Enfamil® Gentlease® Formula

If your baby’s tummy has been extra fussy, this switch may be worth a closer look.

What You'll Learn Today

  • Enfamil Gentlease is a sensitive formula designed for babies with gas and fussiness.
  • Parents often switch to Gentlease when standard formula seems to upset their baby’s tummy.
  • A formula change may help with gas, but every baby responds differently, and results are not guaranteed.
  • Gentlease, NeuroPro® Gentlease, and Optimum™ Gentlease are related but not identical formulas.

What Is Enfamil Gentlease Formula?

Enfamil Gentlease is an infant formula made for gassy and fussy babies. It’s a milk-based formula that has a unique carbohydrate blend and easy-to-digest proteins, which makes Gentlease a gentle formula for your baby’s digestive system.

It’s just one part of Enfamil’s sensitive formula lineup, which is designed with your baby’s comfort in mind.

Why Do Parents Switch to Gentlease Formula?

Parents usually switch to Gentlease formula when their baby seems uncomfortable, and they want to try a formula made for more sensitive digestion. Gas and fussiness are two of the biggest reasons families start looking into this option.

Gentlease baby formula may also be a good choice if you think the baby may have a sensitivity to standard formula.

What to Expect When Switching to Enfamil Gentlease Formula

It’s totally normal for there to be an adjustment period when switching formula! Some babies adjust quickly, while others need a few days to settle into their new routine.

Here are some of the changes you might notice as baby gets used to Enfamil Gentlease formula:1

  • Changes in stool patterns: Your baby may have looser, firmer, more frequent, or less frequent stools as they adjust.
  • Overall comfort: You may notice your baby seems calmer, more settled, or easier to soothe after feeding.
  • Less gas and bloating: Gas may lessen if Gentlease is a better fit for your baby’s digestion.

You might be wondering—does switching formula help with gas? That’s hard to answer. In some cases, babies see great improvement. But in others, it can take time. It can take a little patience to see whether Gentlease is the right fit.

How Does Gentlease Formula Help with Gas and Fussiness?

Gentlease is designed with features that may support easy digestion and feeding tolerance. Enfamil uses evidence-based nutrition to make sure Gentlease and all other formulas are nutritionally complete for little ones.

What Makes Gentlease Easy to Digest?

Gentlease is designed to have easy-to-digest proteins. For babies who seem uncomfortable after feeds, that gentle approach may help support a smoother feeding experience.

Is Enfamil Gentlease formula lactose-free? Not entirely, but it does have a unique carbohydrate blend to help support digestive comfort.

How Ingredients Support Sensitive Tummies

Gentlease is nutritionally complete, which means it is made to provide the nutrition and ingredients babies need while also supporting sensitive stomachs. It also has DHA, which supports healthy brain development as your baby grows.2

Gentlease vs NeuroPro Gentleas vs Optimum Gentlease

Want to compare Enfamil Gentlease vs Enfamil NeuroPro Gentlease vs. Enfamil Optimum Gentlease? Here’s a table that covers the main differences:

Enfamil GentleaseEnfamil NeuroPro GentleaseEnfamil Optimum Gentlease
Expert-Recommended DHA for brain development
Gentle, Easy-to-Digest Proteins designed to help reduce fussiness, crying, gas & spit-up in 24 hours*
MFGM Components composed of proteins and fat from Whey Protein Concentrate 
Exclusive HuMO6® Premium Immune & Gentle Blend with 2'-FL HMO (Human Milk Oligosaccharide) for Immune Health 
Lactoferrin for Immune Support—a key protein also found in breast milk & colostrum  
LnNT an HMO that helps support immune health and is also found in breast milk  

*Studied before the addition of 2'-FL and LnNT

2'-Fucosyllactose and Lacto-N-neotetraose Human Milk Oligosaccharides. Not from human milk

Has 20% the lactose of a full-lactose routine milk-based formula

To sum up, all three Gentlease formulas provide gentle nutrition designed to address gas and fussiness.

The primary difference between regular Gentlease and NeuroPro Gentlease is that NeuroPro Gentlease includes additional brain-supporting components, including milk fat globule membrane (MFGM), along with a prebiotic blend to help ease stooling discomfort. Optimum Gentlease also contains MFGM and adds lactoferrin for immune support.

If you’re considering switching among Gentlease, NeuroPro Gentlease, and Optimum Gentlease, your pediatrician can help you decide which may better fit your baby’s needs.

When Might Gentlease Be a Good Fit for Your Baby?

The most common indicators that Enfamil Gentlease formula may be worth asking about include:

  • Persistent gas
  • Fussiness after feeding
  • Mild feeding sensitivities

Tips for Introducing Gentlease to Your Baby's Diet

Before switching formulas, develop a game plan with your pediatrician. They may suggest a gradual introduction by mixing Gentlease with their current formula, or they might greenlight you to try it right away. While many babies have no issues switching formulas, it’s also not uncommon for babies to take 3 to 5 days to become used to a new formula.

  • Try to introduce Gentlease when your baby is hungry.
  • Try to be positive during feeding times, as babies can pick up on your reactions, such as from facial expressions and the sound of your voice. Let them know it’s going to be yummy and feel good in their tummy!
  • When you are ready to start weaning your baby, check out these additional tips for introducing your baby to solid foods with Gentlease!

Where to Find Gentlease Formula and Savings

Trying to choose the right formula can feel overwhelming, especially when your baby is gassy or fussy. Enfamil Family Beginnings is here with helpful resources, product guidance, and support for families who are figuring out what works best for their baby. Join today to get practical help as you navigate feeding with a little more confidence.

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All information on Enfamil, including but not limited to information about health, medical conditions, and nutrition, is intended for your general knowledge and is not a substitute for a healthcare professional's medical identification, advice, or management for specific medical conditions. You should seek medical care and consult your doctor or pediatrician for any specific health or nutrition issues. Never disregard professional medical advice or delay seeking medical treatment, care, or help because of information you have read on Enfamil.