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Enfamil Optimum Infant Formula 20.5oz Case of 4
Enfamil Optimum baby formula container with a bottle on a gray background
Enfamil Optimum infant formula can with text about Lactoferrin on a light background
Enfamil Optimum baby formula packaging with a bottle on a white surface, featuring immune supporting nutrition components.
Nutritional label with clinically tested ingredients on a blue background
Enfamil Optimum products including a box, can, and bottles on a white background.
Enfamil Optimum formula container with a parent and child in the background
Makes 132 4fl oz bottles
[52002350825839
[52002350825839
#1 Trusted BrandWhat to Expect Mom Must-Have 2025What to Expect Feeding 2025Best of Babycenter 2025

Enfamil® Optimum™ (Enspire) Infant Formula test Powder - 20.5 oz Tub (Case of 4)

For our nutrition closest to breast milk

$187.96
In Stock
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Earns 1880 rewards points with purchase

Format

Format
Liquid
Powder

Type

Tub
Refill

Size

20.5 oz Tub

$47.99

20.5 oz Tub (Case of 4)

$187.96

Ships free
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Enfamil Optimum (Enspire) Infant Formula

test Introducing Enfamil Optimum, formerly known as Enfamil Enspire Optimum—now with a fresh new look but the same trusted nutrition for your little one.

Enfamil Optimum is designed to be our closest formula to breast milk, it has lactoferrin, a key protein found in colostrum and breast milk, and a dual HMO blend.

Perfect for combo feeding, Enfamil Optimum is ideal for supplementing breastfeeding, ensuring your baby gets essential nutrients while providing parents with convenience and peace of mind.

Enfamil Optimum has 2'FL & LnNT, two of the most abundant HMOs that are naturally present in breastmilk, to nourish their immune health.

With NO artificial growth hormones, NO artificial colors or flavors, and a NON-GMO† formula, Enfamil Optimum has complete nutrition for babies through 12 months. Give your baby the best start with Enfamil—trusted by parents†, backed by science.

†Added as an ingredient.

‡Not made with genetically modified ingredients, but trace amounts of genetically engineered materials may be present in the product from manufacturing environments and process sources.

§Among those who have a preference; based on the 2023 survey by AMC Global.

Available Formats and Sizes

Enfamil Optimum Infant Formula is available in powder form in tubs of 20.5 oz and 27.4 oz for your convenience and 30 oz refill boxes with 100% recycled paperboard to help us reduce environmental impact. You can also get Enfamil Optimum Infant Formula in cases of 4.

NEW LOOK, SAME TRUSTED FORMULA: Enfamil Optimum, formerly Enspire Optimum, has a fresh new name and look, while offering the same great nutrition for your little one.
OUR CLOSEST FORMULA TO BREAST MILK: Enfamil Optimum is the first and only leading brand to have lactoferrin†, also found in breastmilk & colostrum.
PERFECT FOR COMBO FEEDING: Ideal for supplementing breastfeeding, Enfamil Optimum offers essential nutrients for baby while giving parents peace of mind and convenience.
PREMIUM IMMUNE BLEND: Lactoferrin and a dual HMO blend (2'FL & LnNT), key ingredients clinically shown to support baby's developing immune system.
PEACE OF MIND: Optimum contains NO artificial growth hormones, NO artificial colors or flavors, and is NON-GMO, offering complete nutrition for babies through 12 months.
Pediatrician Recommended
TRUSTED BY PARENTS & PEDIATRICIANS‡: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians§ & Parents and the #1 trusted brand by pediatricians for brain-building and Immune Support.
Enfamil reduces its environmental impact by using 100% recycled paperboard for our refill boxes.

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